一、个人简介

董现玲，博士，副教授，硕士生导师，中共党员，毕业于马来西亚博特拉大学，《Cancer Imaging》、《Computers in biology and medicine 》等杂志审稿人，河北省数理医学学会健康大数据与人工智能专委会委员。现任医工教研室主任、 医工系教工第一支部书记。作为负责人立项校级一流本科课程1项，高教学会十四五教改课题1项，教育部产学协同育人项目2项，教育厅教改课题1项，省一流课程1门。主持并参与国家级课题1项，省级课题5项，厅局级多项，发表多篇学术文章，其中SCI收录20余篇，EI收录2篇，出版著作2部，软著4项。

二、研究方向：

1.医学图像处理以及单光子发射断层成像理论和仿真技术研究；

2.基于深度学习和影像组学的癌症诊断、疗效评估与预后预测；

3. 基于机器学习和EEG的认知障碍诊疗技术研究

三、工作基础：

1、参与课题：

[1] 国家自然科学青年基金项目，“老年遗忘型轻度认知障碍执行功能的神经机制及靶向数字干预研究”，2024-2026，主研人，项目编号：32300931；

[2] 河北省自然科学基金精准医学联合基金培育项目，“老年遗忘型轻度认知障碍执行功能的脑神经机制及指标体系构建”，2022-2025，第二主研人，项目编号：C2022406010；

[3] 河北省高等教育教学改革研究与实践项目，“面向生物医学工程应用型转型专业的实验教学体系构建”，2024-2026，第一主研人，项目编号：2023GJJG322。

[4] 河北省引进留学人员资助项目，“基于深度学习和影像组学预测非小细胞肺癌预后的研究”，2022-2025，第一主研人，编号：C20220107。

[5] 教育部产学合作协同育人项目，“正电子发射计算机断层成像原理实验项目开发及相应资源库建设”，2022-2024，第一主研人，编号：220600562284542；

[6] 教育部产学合作协同育人项目，“基于医学影像和人工智能的Python语言应用案例教学研究”，2022-2023，第二主研人，编号：220607027272033；

[7] 河北省科技厅引智项目，“基于PET/CT头颈癌肿瘤纹理分析及预后评估研究”，2020-2021；

[8] 河北省教育厅青年科学自然基金项目，“基于SPECT/CT 深度卷积神经网络的肺结节自动识别技术”，2018-2021，第一主研人，项目编号：NQ2018066，已结题；

[9] 承德医学院高层次人才启动项目，“肺癌断层成像中巴特沃斯窗参数优化设计研究”，2018-2021，第一主研人，项目编号：201802；

[10] 教育部人文社会科学研究规划青年基金，“基于机器学习的老年轻度认知障碍执行功能多模态评估指标体系构建与精准化认知干预研究”，编号：23YJCZH130，2023-2026，第五；

[11] 河北省高等教育学会高等教育科学研究“十四五”规划课题，基于虚拟仿真的医学影像技术类课程实验教学改革探究——以PET成像技术为例， 2021-2023，第一主研人，项目编号：GJXH2021-126；

[12] 河北省教育厅青年科学自然基金项目，“基于超声图像的卷积神经网络对甲状腺疾病的识别研究”，2019-2021，第二主研人，项目编号：NQ2019055；

2、最能代表申请人贡献和水平的论文、著作、设计、专利等，并注明发表时间、刊物名称、专利号等；

文章：

[1] Li Shuyan, Xie Jiayi, Liu Jinghua,Wu Yanjun, Wang Zhongxiao,Cao Zhendong,Wen Dong,Zhang Xiaolei,Wang Bingzhen,Yang Yifan,Lu, Lijun, Dong Xianling∗. Prognostic Value of a Combined Nomogram Model Integrating 3-Dimensional Deep Learning and Radiomics for Head and Neck Cancer. Journal of Computer Assisted Tomography, 2024. DOI: 10.1097/RCT.0000000000001584.

[2] Bingzhen Wang, Jinghua Liu, Xiaolei Zhang, Zhongxiao Wang, Zhendong Cao, Lijun Lu, Wenbing Lv, Aihui Wang, Shuyan Li, Xiaotian Wu , Xianling Dong*. Prognostic value of 18F-FDG PET/CT-based radiomics combining dosiomics and dose volume histogram for head and neck cancer[J]. EJNMMI Research 2023,13(1):14. https://doi.org/10.1186/s13550-023-00959-6 

[3] Xiaolei Zhang, Xianling Dong*, M. Iqbal bin Saripan, Dongyang Du, Yanjun Wu, Zhongxiao Wang, Zhendong Cao, Dong Wen, Yanli Liu, Mohammad Hamiruce Marhaban. Deep learning PET/CT-based radiomics integrates clinical data: A feasibility study to distinguish between tuberculosis nodules and lung cancer[J]. Thoracic Cancer, 2023 ,14(19):1802-1811. https://doi.org/10.1111/1759-7714.14924 

[4] Wang, Zhongxiao, Xiong, Tianyu, Jiang, Mingxin, Cui, Yun, Qian, Xiaosong, Su, Yao, Zhang, Xiaolei, Xu, Shiqi, Wen, Dong, Dong, Xianling*, Yang, Minfu* and Niu, Yinong*. Automatic prediction model of overall survival in prostate cancer patients with bone metastasis using deep neural networks[J]. Oncologie, 2023,25(5): 519-527. https://doi.org/10.1515/oncologie-2023-0115

[5] Shuyan Li , Jinghua Liu, Zhongxiao Wang, Zhendong Cao, Yifan Yang, Bingzhen Wang, Shiqi Xu , Lijun Lu, M. Iqbal Saripan, Xiaolei Zhang, Xianling Dong* , Dong Wen. Application of PET/CT-based deep learning radiomics in head and neck cancer prognosis: a systematic review[J]. Radiology Science, 2022 ,1(1):11-25. https://doi.org/10.15212/RADSCI-2022-0006

[6] Wu, Yanjun, Xianling Dong, Guochao Shi, Xiaolei Zhang, and Congzhe Chen. 2022. "Crime Scene Shoeprint Image Retrieval: A Review[J]. Electronics 11( 16): 2487. https://doi.org/10.3390/electronics11162487 

[7] Dong Wen, Wenlong Jiao, Xiaoling Li, Xianglong Wan, Yanhong Zhou, Xianling Dong, Xifa Lan, Wei Han, The EEG signals encryption algorithm with K-sine-transform-based coupling chaotic system,Information Sciences,2023,622: 962-984, https://doi.org/10.1016/j.ins.2022.12.001

[8] Wen, Dong and Yuan, Jingpeng and Li, Jingjing and Sun, Yue and Wang, Xianpu and Shi, Ruihang and Wan, Xianglong and Zhou, Yanhong and Song, Haiqing and Dong, Xianling and Xu, Fangzhou and Lan, Xifa and Jung, Tzyy-Ping, "Design and Test of Spatial Cognitive Training and Evaluation System Based on Virtual Reality Head-Mounted Display With EEG Recording," in IEEE Transactions on Neural Systems and Rehabilitation Engineering, vol. 31, pp. 2705-2714, 2023, doi: 10.1109/TNSRE.2023.3283328.

[9] W Wen Dong, Pang Zhenhua, Wan Xianglong, Li Jingjing, Dong Xianling, Zhou Yanhong. Cross-task-oriented EEG signal analysis methods: Our opinion[J]. Frontiers in Neuroscience, 2023, 17: 1153060.

[10] Wen, Dong and Liang, Bingbing and Li, Jingjing and Wu, Lingyu and Wan, Xianglong and Dong, Xianling and Lan, Xifa and Song, Haiqing and Zhou, Yanhong, "Feature Extraction Method of EEG Signals Evaluating Spatial Cognition of Community Elderly With Permutation Conditional Mutual Information Common Space Model," in IEEE Transactions on Neural Systems and Rehabilitation Engineering, vol. 31, pp. 2370-2380, 2023, doi: 10.1109/TNSRE.2023.3273119.

[11] Dong Xianling, Xu S, Liu Y, Wang A, Saripan MI, Li L, Zhang X, Lu L. Multi-view secondary input collaborative deep learning for lung nodule 3D segmentation. Cancer Imaging. 2020 ,20(1):53. （中科院二区, IF=4.9）.

[12] Dong Xianling, M.I. Saripan, R. Mahmud, S. Mashohor, S.Hashim and Aihui Wang. Characteristic of SIEMENS Symbia T SPECT Camera in Monte Carlo Simulation Environment[J], Pakistan Journal of Nuclear Medicine，2018,8(1):18-26.

[13] Dong Xianling, Saripan, M. I., R. Mahmud, S. Mashohor, Aihui Wang. Determination of the Optimum Filter for Tc-99m SPECT Breast Imaging Coupled with Wire Mesh Collimator[J]. Pakistan Journal of Nuclear Medicine, 2017, 7(1):19-24.

[14] Haining Liu, Xianling Dong, Jingjing Wang, Haihong Liu, Yanli Liu, Buxin Han & Lianxin Sun (2022) Age-related positivity effect of emotional attention: time and frequency domain, Psychology, Health & Medicine

[15] Liu Haining, Liu Yanli, Dong Xianling, Liu H, Han B. Effect of Cognitive Control on Age-Related Positivity Effects in Attentional Processing - Evidence From an Event-Related Brain Potential Study[J]. Frontiers in Psychology. 2021 ;12:755635.

[16] Hussain, K.; Alnafea, M.A.; Saripan, M.I.; Mahboub, D.; Mahmud, R.; Wan Adnan, W.A.; Xianling, D. An Innovative Concept of a 3D-Coded Aperture Imaging System Proposed for Early Breast Cancer Detection. Diagnostics 2022, 12, 2529.

[17] Dong Wen, Rou Li, Hao Tang, Yijun Liu, Xianglong Wan, Xianling Dong, M. Iqbal Saripan, Xifa Lan, Haiqing Song,Yanhong zhou. Task-State EEG Signal Classification for Spatial Cognitive Evaluation Based on Multiscale High-Density Convolutional Neural Network[J]. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2022, 30: 1041-1051.

[18] Wen Dong, Xu Jian, Wu Zhonglin, Liu Yijun, Zhou Yanhong, Li Jingjing, Wang Shaochang, Dong Xianling, Saripan M. Iqbal, Song Haiqing. The Effective Cognitive Assessment and Training Methods for COVID-19 Patients With Cognitive Impairment[J]. Frontiers in Aging Neuroscience. 2022,13:827273.

[19] Dong Wen, Rou Li, Mengmeng Jiang, Jingjing Li, Yijun Liu, Xianling Dong, M. Iqbal Saripan, Haiqing Song, Wei Han, Yanhong Zhou,Multi-dimensional conditional mutual information with application on the EEG signal analysis for spatial cognitive ability evaluation,Neural networks,2022,148:23-36. (SCI)

[20] Wen Dong, Yao Wang, Xu Jian, Wang Shaochang, Zhong Yingzhu, Chen Hongqian, Dong Xianling, Saripan M. Iqbal, Zhou Yanhong. Electronic Science Games Used to Enhance Cognitive Ability: Opinion of Design From Personalization and Adaptation[J]. Frontiers in Aging Neuroscience,2022,13.

[21] Dong Wen, Zihao Cheng, Jingjing Li, Xinxiang Zheng, Wang Yao, Xianling Dong, M. Iqbal Saripan, Xiaoli Li, Shimin Yin, Yan hong, Zhou. Classification of ERP signal from amnestic mild cognitive impairment with type 2 diabetes mellitus using single-scale multi-input convolution neural network[J]. Journal of neuroscience methods, 2021, 363: 109353.

[22] Yijun Liu, Xiaodong Xu, Yanhong Zhou, Jian Xu, Xianling Dong, Xiaoli Li, Shimin Yin, Dong Wen*. Coupling feature extraction method of resting state EEG signals from amnestic mild cognitive impairment with type 2 diabetes mellitus based on weight permutation conditional mutual information[J]. Cognitive Neurodynamics, 2021, 15(6): 987-997.

3、出版著作：

[1] 单光子发射断层成像及其仿真技术研究: 英文，吉林大学出版社，ISBN：9787569264272，主编，2020年11月；

[2] WISTAR大鼠的脊髓形态学图谱，吉林大学出版社，ISBN：9787569279399，副主编；

4、软件著作权

[1] PET 虚拟仿真成像教学系统，登记号：2020SR1033468，2020.9.3；

[2] PET-CT医学影像勾画标注软件，登记号：2021SR1693409, 2021.11.10；

[3] MRI增强序列分析软件，登记号：2021SR1693408，2021.11.10。

[4] 声速测量仿真实验软件，登记号：2022SR1491091，2022.11.10

5、获奖

[1] “承医多多岛”学习与生活用品共享交易平台 共青团河北省委青年发展部、省级三等奖，2021.12

[2] 《基于Ubuntu的高校科普基地智慧讲解机器人 (以我校中医文化长廊为例)》 河北省大学生课外学术科技作品竞赛三等奖，2023.06